Five Biggest Celeb Breakups of 2012 PHOTOS

Johnny Depp and Vanessa Paradis

They never married but had solid 14 years together. However, rumors of a split had been surfacing for some time now.  The couple have two kids together: Lily-Rose, 13, and Jack, 9.

Courtney Cox and David Arquette

Courtney and David split due to "irreconcilable differences" and filed for divorce in June 2012. They have an eight-year-old daughter Coco whose custody they both seek.

Sofia Vergara and Nick Loeb

Sofia split with her boyfriend of two years, Nick Loeb who she met a Golden Globes party in 2010.

Eva Longoria and Eduardo Cruz

Eduardo Cruz was the man who made Eva smile after her nasty divorce from cheating husband Tony Parker. However, luck didn’t seem to be on their side as they ended up splitting by what they called a "mutual decision" to go their separate ways.

Heidi Klum and Seal

Heidi Klum and Seal’s announcement of separation after nearly seven years of marriage was a great shock to many. Klum and Seal got engaged in 2004 and married on May 10, 2005. They have three children together. The couple renewed their vows to one another each year on their anniversary in front of family and friends until their decision to split.