A bomb ripped through a vehicle in Pakistan's northwestern tribal belt on Wednesday, killing eight civilians including two children, officials said.
The bomb exploded in Sepoy village in Orakzai district, said senior administration official Zakir Hussain.
"It was remote-controlled bomb planted on the road. The bomb exploded near a pick-up van carrying passengers," Hussain told AFP.
The blast killed eight people, including two women, an 11-year-old boy and a three-year-old girl, he said, adding that four people were wounded.
Intelligence officials confirmed the blast and the casualties.
Orakzai is one of seven districts in Pakistan's tribal belt on the Afghan border that is home to Taliban and Al-Qaeda strongholds. Washington has dubbed the area the most dangerous region on Earth.