The CDC and Frontier Airlines said Wednesday that the newly infected health care worker flew from Cleveland to Dallas-Fort Worth on Monday.
Officials are notifying the 132 passengers on the same flight with the woman, the second person diagnosed in Dallas.
Infected patients are not considered contagious until they have symptoms. Symptoms of Ebola include a fever (greater than 101.5°), a severe headache, muscle pain, weakness, diarrhea and vomiting.
The airplane's crew confirmed that the nurse appeared to have no symptoms during the flight. However, the CDC is asking the passengers to call the health agency so they can be monitored.
The unidentified woman reported a fever Tuesday. She was in isolation within 90 minutes and her house and car are being cleaned today.
"We are looking at every element of our personal protection equipment and infection control in the hospital," said Dr. Daniel Varga, chief clinical officer for Texas Health Resources, which operates Texas Health Presbyterian Hospital Dallas.
The head of the CDC, Dr. Tom Frieden, acknowledged that the government has not been aggressive enough containing the virus that spread from the infected patient.
"We could've sent a more robust hospital infection control team and been more hands-on with the hospital from day one about exactly how this should be managed," he said Tuesday.
The second case may help health officials determine where the infection control procedures can be improved.