A suicide car bomber has struck a joint Afghan-Nato military base in eastern Paktia province, say officials.
Nato spokesman Maj Adam Wojack said there were a number of casualties among the Afghan military personal.
No members of the Nato-led International Security Assistance Force (Isaf) were reported to have been injured, said Maj Wojack.
Foreign forces are due to withdraw from Afghanistan by 2014, which has sparked fears of a surge in violence.
An Isaf spokesman told AFP the combat outpost in Zurmat district was attacked by "insurgents using a vehicle-borne improvised explosive device".
A spokesman for the Paktiya provincial governor told the agency that 10 wounded Afghan soldiers had evacuated.